Exploring design trade-offs for achieving social inclusion in multi-tiered design problems

ABSTRACT

The digital age of the future is ‘not out there to be discovered’, but it needs to be ‘designed’. The design challenge has to address questions about how we want to live, work, and learn (as individuals and as communities) and what we value and appreciate, e.g.: reflecting on quality of life and creating inclusive societies. An overriding design trade-off for the digital age is whether new developments will increase the digital divide or will create more inclusive societies. Sustaining inclusive societies means allowing people of all ages and all abilities to exploit information technologies for personally meaningful activities. Meta-design fosters the design of socio-technical environments that end-user developers can modify and evolve at use time to improve their quality of life and favour their inclusion in the society. This paper describes three case studies in the domain of assistive technologies in which end users themselves cannot act as end-user developers, but someone else (e.g.: a caregiver or a clinician) must accept this role requiring multi-tiered architectures. The design trade-offs and requirements for meta-design identified in the context of the case studies and other researchers’ projects are described to inform the development of future socio-technical environments focused on social inclusion.     

中国废钢资源发展战略研究

 为提高中国钢铁工业的废钢比,推动钢铁工业的绿色发展,分析了中国废钢资源的概况、废钢行业技术发展现状和钢铁工业废钢利用的现状,并对中国未来废钢资源量进行预测。在此基础上,针对中国废钢资源的发展提出了3条战略判断和6条政策建议。     

基于物联网的智慧林业可持续发展策略研究

随着我国科技的不断进步,在“互联网+”大数据的背景下,林业的智慧化发展是必经之路。虽然我国智慧林业的发展已经取得了一定的突破,但是仍然存在着许多问题。基于此,文章在物联网技术的基础上,对智慧林业的可持续发展策略进行探讨。     

An e-government framework for assessing readiness for public sector e-procurement in a lower-middle income country

ABSTRACT

Governments globally are leveraging information and communication technology (ICT) growth towards improving the quality of public procurement services for socio-economic development. However, the extent of its application differs across nations. Notwithstanding the extant theoretical and empirical literature on IT for development, knowledge on how to assess readiness for adopting a full e-procurement system in the public sector of lower and lower-middle income countries (LMICs) begs for understanding. With the narrative of Ghana, we address this gap by drawing on the institutional and economic theory and the United Nations E-Government Development Index towards a holistic framework beyond the dyad of linear website functionalities and internet focus of prior e-government adoption models. Elite interviews gathered from multiple cases from Ghana’s public sector reveals the key readiness determinants for a full public sector e-procurement system. This study has significant implications for shaping the process-oriented management of government e-procurement projects towards socio-economic development in LMICs amid their complex institutional and socio-technical environments.     

面向电网实时运行风险的快速定级方法研究及应用

为满足电网运行实时风险评估时效性要求,解决电网运行实时风险评估与定级中效率与精度两者间协调的问题,在当前国家和主要电网企业规定的电网运行事故定级标准基础上提出了一种快速定级方法。快速定级方法充分考虑了电网运行实际特性,采取数据治理和算法重构两方面主要措施,对原判定方法进行优化处理。通过数据治理,大幅降低了对外部数据的依赖性,并取消了部分不必要的输入数据。采用算法重构,进一步将运行风险定级与实际业务流程紧密联系。以该快速定级方法为核心,构建了支撑电网运行风险分析与事故处置的实时运行风险管理系统,介绍了该系统的功能框架与系统架构。最后结合该系统在贵阳的实际应用情况,分析了快速定级方法的实际使用效益。     

ACE2, the Receptor that Enables Infection by SARS-CoV-2: Biochemistry,Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators

Angiotensin converting enzyme 2 (ACE2) is the human receptor that interacts with the spike protein of coronaviruses, including the one that produced the 2020 coronavirus pandemic (COVID-19). Thus, ACE2 is a potential target for drugs that disrupt the interaction of human cells with SARS-CoV-2 to abolish infection. There is also interest in drugs that inhibit or activate ACE2, that is, for cardiovascular disorders or colitis. Compounds binding at alternative sites could allosterically affect the interaction with the spike protein. Herein, we review biochemical, chemical biology, and structural information on ACE2, including the recent cryoEM structures of full-length ACE2. We conclude that ACE2 is very dynamic and that allosteric drugs could be developed to target ACE2. At the time of the 2020 pandemic, we suggest that available ACE2 inhibitors or activators in advanced development should be tested for their ability to allosterically displace the interaction between ACE2 and the spike protein.     

中国无机盐工业发展现状及展望

建国70 a以来中国无机盐工业发展迅猛,取得了巨大成就,中国已成为世界上最大的无机盐生产、出口和消费国。分析了中国无机盐工业生产现状和进出口情况,指出行业存在大宗产品产能过剩、产品精细化率偏低、产业集中度和资源配置率偏低、矿产资源保障能力不足、节能减排任务重、自主创新能力弱等问题,并提出未来发展建议及发展方向。新能源用无机材料、无机粉体功能材料、5G通迅用无机材料、电子化学品和电镀化学品等专用化学品将是未来无机盐工业发展的热点。随着产业链现代化水平的不断提升,将会逐渐实现行业规模化、绿色发展与安全生产。     

低渗透油田开发调整技术对策研究

低渗透油田有很多特点,比如油气比较多,油气藏类型也很多,分布区域比较广。如果可以比较合理科学的开发低渗透油田,对我国石油开采能够产生极为积极的影响。基于此,主要讨论了目前低渗透油生产的具体特征,使用油藏工程的方法,以此调整技术,让地层能量得以保持,尽量减缓产量递减的情况。并且探索了开发效果评价以及开发政策界限,以此提高油田的采收率,分析了剩余油的分布特征影响因素。     

油藏开发地质勘探的常见问题分析

就油藏开发地质勘探的常见问题进行分析,从油藏开发的分类、油藏开发程序以及油藏储量计算等方面综合考虑影响油藏开发的因素,为现实油藏开发工程提供理论依据,提升油藏开发技术水准。     

水泥窑余热发电系统用耐磨材料的研制与应用

本研究针对水泥窑余热发电系统的工作条件,根据耐磨材料的损毁机理,采用高铝矾土、煅烧氧化铝粉、黏土、硅微粉等为原料,以磷酸二氢铝为结合剂,以铝酸钙水泥为促硬剂,通过添加掩蔽剂和优化配料工艺,制备了水泥窑余热发电系统用耐磨材料,并对不同处理温度对耐磨材料的性能影响进行了分析。结果表明增强骨料与基质的结合能力有利于耐磨性的提高,磷酸及磷酸盐与氧化铝之间会随着温度的升高生成不同的磷酸铝相,都能够起到结合作用,比采用水泥结合更有利于提高材料在不同温度下的强度和耐磨性。使用结果表明,制备的耐磨材料施工性能优良,凝结硬化时间适当,强度高,抗冲刷性能好,在水泥窑余热发电系统中取得了良好的使用效果。